Dr. Anup Kumar Ghosh
Designation : Professor
Department : MEDICAL MICROBIOLOGY
kumarghosh.anup@pgimer.edu.in

 

 
 :: Contact Details
  Phone No.    :   7087008062
  Ext No.        :   5156
 :: Educational Qualification
  Graduation :   BSc from Calcutta University Kolkata in year 1986
  Post Graduation :   MSc from Sagar University MP in year 1992
  Other Qualification.(1)      :   PhD from PGIMER Chandigarh in year 2000
     
 :: Area of Interest
       Area Of Interest       :
  1. Use of MALDI TOF MS in fungal diagnostics.
  2. Epidemiology, and pathogenesis of fungal keratitis.
  3. Drug resistance in Candida tropicalis and Candida auris infection
  4. Developments of rapid diagnostics for the diagnosis of fungal infections
  5. Genetic susceptibility of invasive fungal infections
  6. Epidemiology and genetic susceptibility of Vulvovaginal candidiasis
     
 :: Research & Projects
      Extramural Projects       :
  • PI in DBT North East Twinning project, 21L (2012-2015)
  • PI in DST-SERB grant 43 lakh (started 2017) entitled “Use of MALDI-TOF MS for rapid identification of    medically important fungi, detection of resistant isolates and creation of in-house database for Indian isolates”.
  • PI in DBT North East Twinning project, 22.5L (started 2017) entitled “Systematic epidemiological study and rapid diagnosis of infectious keratitis in north east and north India”.
      Departmental / P.G.I.
      Projects      
:
  • PI in several PGI Intramural Grant, 5L each (started 2015,2016,2017,2018,2019)
      Awards & Honours       :
  • Best publication in Add Prof category, awarded by PGIMER in the year 2018.
  • Best publication in Assoc Prof category, awarded by PGIMER in the year 2016
  • ICMR ‘Travel Grant Award’ to attend 117th Annual Meeting of the American Academy of Ophthalmology (AAO) at New Orleans USA, in November, 2013.
  • Best poster award in 9th SIHAM conference at Siliguri, West Bengal from 10-12th February, 2012.
  • ASM travel Grant - Welcome Borough Award, one of the best posters in 9th ASM “Candida and Candidiasis”, New Jersey, USA from 24th -28th March 2008.
  • Senior Research Fellowship (SRF) Award from Indian Council of Medical Research in April, 1996.
  • Gold Medal for securing 1st class 1st position in MS in Applied Microbiology and Biotechnology from Dr. HS.Gour University, Sagar, MP in August-1992.
  • Prof. G.P. Agarwal Young Scientist best research paper award at International conference on Current Status and challenges in Medical and Veterinary Mycology Research in 1996 at Jabalpur, India.
      Member Of Professional
      Bodies      
:
  • ASM (American Society for Microbiology), 2002-present.
  • AAAS (American Association for the Advancement of Science) 2005-2011.
  • ISHAM (International Society for Indian Human and Animal Mycology), 2000-present.
  • SIHAM (Society for Indian Human and Animal Mycology), Life member.
     
 :: Publications(In Vancouver Style)

1.     Ghosh AK*, Rudramurthy SM, Gupta A, Choudhary A, SinghS, Thakur A, Jatana M. Evaluation of liposomaland conventional Amphotericin B in experimental fungal keratitis rabbit model Transl Vis Sci Technol. 2019 (in press)

2.     Paul, Saikat; Singh, Shreya; Chakrabarti, Arunaloke; Shivaprakash, M; Ghosh,Anup*. Stable isotope labeling: An approach for MALDI-TOF MS-based rapiddetection of fluconazole resistance in Candida tropicalisJAntimicrob Chemother. 2019 (in press)

3.      Prakash H, Singh S, Rudramurthy SM, Singh P, MehtaN, Shaw D, Ghosh AK*An aeromycological analysis of Mucorales in indoor and outdoor environments ofnorthern India, Med Mycol. 2019 (inpress)

4.       AmitGupta , Anchal Thakur , Suruchi Gupta , Parul Icchpuchany , Manjari
       Tandon,Jagat Ram , ArunlokeChakrabarti , Anup Ghosh. EarlyVersus Delayed
        Intervention with IntracameralLiposomal Amphotericin B in Recalcitrant    
       Keratomycoses: Experience of aLarge Case Series. J Clin Diagn Res.2019 Mar, Vol-
       13(3)

5.       Paul, Saikat ; Singh, Shreya; Chakrabarti, Arunaloke;Shivaprakash, M; Ghosh,
      Anup
*. Stable isotope labeling: An approach for MALDI-TOF MS-basedrapid
      detection of fluconazole resistance in Candidatropicalis. J Antimicrob Chemother.
      2019 (in press)

6.     Devana SKGupta VGMavuduru RSBora GSSharma APParmar KMKumar SMete UKSingh SKMandal AKKakkar NBanerjee NGhosh A.Isolated renal mucormycosis in immunocompetent hosts: Clinical Spectrum andManagement Approach. Am J Trop MedHyg. 2019 Jan 14

7.      Jain NJinagal JKaur HGhosh AGupta SRam JRudramurthy SM. Ocular infection caused by Hormographiella aspergillata: A case report and review of literature. J Mycol Med.2019 Jan 7

8.      SaikatPaul, Pankaj Singh, Savitri Sharma, GS Prasad, Shivaprakash M. Rudramurthy,Arunaloke Chakrabarti and Anup K Ghosh*.MALDI -TOF MS based identification ofmelanized fungi is faster and reliable after the expansion of in-house database.Proteomics Clin Appl ,2018  Aug 23.

9.      Raees A.Paul, Shivaprakash M. Rudramurthy, Manpreet Dhaliwa1, Pankaj Singh, Anup K. Ghosh, Harsimran Kaur, SubhashVarma, Ritesh Agarwal, Arunaloke Chakrabarti. Voriconazole resistance in clinical and environmental isolates of Aspergillus flavus: frequency and investigation into the role of multidrug efflux pumps.Antimicrob Agents Chemother.2018 Oct 24;62(11)

10.   ShamanthA.Shankarnarayan, Shivaprakash M. Rudramurthy, Arunaloke Chakrabarti, HarsimranKaur, Dipika Shaw, Saikat Paul, Nandini Sethuraman Anup K Ghosh*. Molecular Typing and Antifungal Susceptibility of Candida viswanathii, India. EmergInfect  2018 Oct;24(10):1956-1958

11.   Prakash HGhosh AKRudramurthy SMSingh PXess ISavio JPamidimukkala UJillwin JVarma SDas APanda NKSingh SBal AChakrabartiA. A prospective multicenterstudy on mucormycosis in India: Epidemiology, diagnosis, and treatment. MedMycol 2018 Aug 1.

12.   A. Chakrabarti, Shivaprakash M Rudramurthy, A.K Ghosh, Harsimran Kaur ,Gastrointestinal mucormycosis in apparentlyimmunocompetent hosts-a review. Mycoses 2018May,31.

13.   P Honnavar1#, A K Ghosh 1, S Paul 1, P Singh 1,S Dogra2, A Chakrabarti 1, S M Rudramurthy 1*. Identification of Malassezia species by MALDI-TOF MSafter expansion of database.  DiagnosticMicrobiology and Infectious Disease,2018:May 29

14.   ShivaprakashM Rudramurthy, Megha Sharma, Madhubala Sharma, Pankaj Rawat, Anup K Ghosh, Lakshmishree V, RiteshAggarwal, Meenu Singh, Arunaloke Chakrabarti*. Reliable differentiation of Pneumocystis pneumonia fromPneumocystis colonization by quantification of Major Surface Glycoprotein geneusing real-time polymerase chain reaction. Mycoses2017 Sep 25. doi: 10.1111/myc.12708.

15.   Saikat Paul, Pankaj Singh,Shivaprakash M. Rudramurthy, Arunaloke Chakrabarti, Anup K. Ghosh1*.MALDI-TOF-MS: Protocol standardization and database expansion for rapididentification of clinically important moulds. Future Microbiol 2017 Oct 27.doi: 10.2217/fmb-2017-0105.

16.   Hariprasath Prakash; Shivaprakash Mandya Rudramurthy; GandhamS Prasad; Anup K Ghosh; Milner KumarM; Chandan Badapanda; Arunaloke Chakrabarti. Apophysomyces variabilis: draftgenome sequence and comparison of predictive virulence determinants with othermedically important Mucorales. BMC Genomics2017:18 (1), 736

17.   Wangsanut T, Ghosh A,Metzger P, Fonzi W, and Rolfes R. Grf10 and Bas1 regulate de novo AMPbiosynthesis and are implicated in virulence in the human fungal pathogen Candidaalbicans. mSphere(ASM) 2017  Aug 2;2(4). pii: e00161-17. doi: 10.1128/mSphere.00161-17

18.   SaikatPaul, Pankaj Singh, Shamanth A S, Shivaprakash M. Rudramurthy, ArunalokeChakrabarti and Anup K Ghosh*. Rapid detection of Fluconazole resistance in Candidatropicalis by MALDI–TOF MS. MedicalMycology 2017, 0, 1–8

19.   ShivaprakashM. Rudramurthy , Arunaloke Chakrabarti *, Raees A. Paul , Prashant Sood ,Harsimran Kaur , Malini R. Capoor , Anupma J. Kindo , Rungmei S. K. Marak , AnitaArora5, Raman Sardana , Shukla Das , Deepinder Chhina, Atul Patel , ImmaculataXess, Bansidhar Tarai, Pankaj Singh and AnupGhosh. Candida auris candidaemia in Indian ICUs: analysis of risk factors. JAntimicrob Chemother 2017; 72: 1794–1801

20.   Ghosh AK, Gupta A, Shivaprakash MR, PaulS, Hallur VK and Chakrabarti A. Fungal keratitis in North India: spectrum ofagents, risk factors and treatment. Mycopathologia2016 Jul 29.

21.   Honnavar P, Prasad G, GhoshA, Dogra S, Handa S, and  RudramurthyS. Malassezia arunalokei sp. nov., anovel yeast species isolated from seborrhoeic dermatitis patients  and healthy individuals from India. J Clin Microbiol 2016 May 4. pii:JCM.00683-16

22.   Singh P†, Paul S†,Shivaprakash MR, Chakrabarti A, Ghosh AK.StressResponse in medically important Mucorales. Mycoses2016 Jun 13. doi: 10.1111/myc.12512

23.   Hariprakash P, GhoshAK, Shivaprakash MR, Raees AP, Gupta S, Negi V, Chakrabarti A. The environmental source of emerging Apophysomyces variabilis infection inIndia. Medical Mycology 2016 Apr 26. pii: myw014

24.   Rastogi V, Honnavar  P, Shivaprakash, M , Umabala  P, Ghosh A, Chakrabarti  A. Molecularcharacterization and antifungal susceptibility of clinical Trichosporonisolates in India. Mycoses 2016, May4. doi: 10.1111/myc.12511.

25.   Ghosh AK, Wangsanut T, Fonzi WA, Rolfes, RJ. The GRF10 homeobox generegulates filamentous growth in human fungal pathogen Candida albicans, FEMS YeastResearch 2015,9 Dec;15(8).

26.   Chakrabarti A,  KaurH, Rudramurthy SM, Appannanavar SB, Patel A, Mukherjee KK, Ghosh A, RayU. Brain abscess due to Cladophialophora bantiana: a review of124 cases, Med Mycol. 2016 Feb 1;54(2):111-9.

27.   Shivaprakash M Rudramurthy, Prasanna Honnavar,Harsimran Kaur,Palash Samanta, Pallab Ray, Anup K Ghosh,Arunaloke Chakrabarti. Molecular identification of clinical Nocardia isolates from India, 2015 J Med Microbiol (In press)

28.   A.K. Ghosh, S. Paul, P. Sood, S.M. Rudramurthy, A. Rajbanshi,T.J. Jillwin, A. Chakrabarti.Matrix-assisted laser desorption ionization time-of-flight mass spectrometryfor the rapid identification of yeasts causing bloodstream infections. Clin Microbiol Infect. 2015 Apr; 21(4):372-8.

29.   Panda A, Ghosh AK, Mirdha BR, Xess I, Paul S, Samantaray JC, Srinivasan A, Khalil S, Rastogi N, Dabas Y. MALDI-TOF mass spectrometry for rapid identification of clinicalfungal isolates based on ribosomal protein biomarkers. J Microbiol Methods. 2014 Dec 23;109C:93-105