Prof. Dheeraj Khurana
Designation : Professor
Department : NEUROLOGY
khurana.dheeraj@pgimer.edu.in

 
 
 :: Contact Details
  Phone No.    :   7087009695
  Ext No.        :   6695
 :: Educational Qualification
  Graduation :   MBBS from DMCH.Ludhiana in year 1992
  Post Graduation :   MD (Med) from DMCH.Ludhiana in year 1996
  Other Qualification.(1)      :   DM (Neurology) from PGIMER. Chandigarh in year 2000
     
 :: Area of Interest
       Area Of Interest       :
  1. Acute Stroke : Thrombolysis, imaging,management and rehabilitation
  2. Multiple Sclerosis : Management and rehabilitation
  3. Neurosonology : Carotid duplex, TCD and its applications


 
     
 :: Research & Projects
      Extramural Projects       :


ACADEMIC


S No

Title

Role

Sponsor

Status

1

SITS SEARES – Safe Implementation of Treatments in Stroke

National Co -ordinator

Non-funded

Ongoing

2

In-hospital database for Multiple Sclerosis - MS Base

Principle Investigator

Non-funded

Ongoing

3

INSTRuCT

I.                     Enhanced Control of Hypertension and Thrombolysis in Stroke Study – ENCHANTED

 

 

II.                   Secondary Prevention By Structured Semi-Interactive Stroke Prevention Package in INDIA (SPRINT INDIA) Study

Principle Investigator

 

George Institute, Hyderabad

 

ICMR

Ongoing

4

Head positioning in Stroke Trials - Head PoST

Principle Investigator

George Institute, Hyderabad

Recruitment Completed – 2017

 

5

FAmily- Led RehabiliTaTion aftEr stroke in INDia -The ATTEND trial

Principle Investigator

George Institute, Hyderabad

Recruitment Completed – 2016

 

6

INTERSTROKE - Importance of Conventional and Emerging Risk Factors for Stroke : A Case Control study

Principle Investigator

SJRI, Bangalore; NIH, USA

Completed - 2014

7

Indo-US Collaborative stroke Registry and Infrastucture development (US-India Bilateral brain research Collaborative partnerships)

Principle Investigator

DBT, India

Completed - 2014

8

Multi Centre Feasibility Pilot study: Safety and Feasibility Assessment of the Neuropath TM IS System in Treatment of Acute Ischemic Stroke-A Pilot Study

Principle Investigator

Brainsgate, Israel

Completed - 2009






Projects in Pipeline:

Sr No

Project

Role

Sponsor

Status

1

RESURRECT (REmote ISchemic conditioning and Fentanyl as an adjUnct to therapeutic hypotheRmia in Hypoxic ischEmic Brain Injury post Cardiac ArresT Study;HIBI Iinitiative)

Co-investigator

DBT

Pipeline

2

Development of low –cost robust hardware and software towards point of care monitoring (POCT) of neuro-glial –vascular interactions (especially inverse neuro-vascular  coupling) during spreading depolarisations in brain trauma using simultaneous  recording of EEG and NIRS.

Co-investigator

DST

Pipeline

 

 


 



DRUG TRIALS

 


  

S No

Title

Role

Sponsor

Status

1

Randomized, double-blind evaluation in secondary stroke prevention comparing the efficacy and safety of the thrombin inhibitor dabigatran etexilate 110 or 150 mg (twice daily) versus acetylsalicylic acid (100 mg once daily) in patients with embolic stroke of undetermined source (RE-SPECT ESUS)

Principle Investigator

Boehringer Ingelheim

ongoing

2

A randomized, double-blind, double-dummy, parallel-group study comparing the efficacy and safety of ofatumumab versus teriflunomide in patients with relapsing multiple sclerosis

Principle Investigator

Novartis

ongoing

3

A randomized, multicenter, placebo-controlled and active reference (glatiramer acetate) comparison study to evaluate the efficacy and safety of BG00012 in subjects with relapsing-remitting multiple sclerosis

Principle Investigator

Biogen Idec

Completed – 2011

4

A Dose-Blind, Multicenter, Extension Study to Determine the Long-Term Safety and Efficacy of Two Doses of BG00012 Monotherapy in Subjects With Relapsing-Remitting Multiple Sclerosis

Principle Investigator

Biogen Idec

Completed – 2017

5

A Randomised, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of desmoteplase in acute ischemic stroke

Principle Investigator

Lundbeck, Denmark

Completed - 2014

6

INTERACT-2 Intensive Blood Pressure Reduction in acute Cerebral Hemorrhage trial

Principle Investigator

George Institute, Hyderabad

Completed - 2012

      Departmental / P.G.I.
      Projects      		 :

S No

Title

Role

Sponsor

Status

1

Development of a immuno-marker based predictive model for early detection and characterization of progressive multiple sclerosis

 

Principle Investigator

PGIMER, Chandigarh

Completed
      Research In
      Progress      		 :

PhD program:

 PhD Scholars

1.Dr. Jitender Gairolla        
                                            
Status: Completed

Jitender comes from the Microbiology background and is an ICMRscholar.His research deals with thegenetic variation analysis of adipokine genes in ischemic stroke. His other fields of research are biomarker and antiplatelet drug discovery in the fieldof stroke, Neuromicrobiology, Development of Aerobic bacterial consortia forbioremediation of synaptic broad spectrum organophosphorus insecticide,Metabolomics profiling using HPLC and LCMS, Genotyping using Real-Time PCR andstatistical analysis. Mr.Gairolla has a significant number of publications torepresent his work and has also presented abstracts in both national andinternational forums.Publication and other details can be followed on https://www.linkedin.com/in/jitender-gairolla-25ba87111/

 

2. Dr.Ashok Jangir                                                            

Status- Completed

Coming from the nursing background, Ashok had been working as a stroke nurse. His research deals with developing a smartphone app to train the caregivers of the bedridden stroke patients so that they can provide care to their patients at home and minimize  the post stroke complications. Mr.Jangir has a number of national and international publications to his name including a book chapter and has also presented his work in various conferences. Most notable ones are:

  1. Presentedresearch poster on “Development, Feasibility And Validation Of “Stroke HomeCare” Application In A Resource Limited Setting: A Proof Of Concept Study” in State-of-the-ScienceStroke Nursing Symposium 2020, (International Stroke Conference 2020)held from 19-2-2020 to 22-2-2020 at Los Angeles, CA. (Poster ID: WP451)
  2.   Presentedresearch paper (oral) on “PostStroke complications and caregivers’ stress among stroke patients in adeveloping country” in ESOC-2019 held at Milan, Italy from 22-24 May 2019. (AbstractNumber: AS14-039)
  3. KumarA, Khurana D, Pttanaik S, Kumar M, Modi M, Kaur S, et.al. “Development,Feasibility and Validation of “Stroke Home Care” Application in a ResourceLimited Setting: A Proof of Concept Study”. Stroke. Feb 2020; 51:AWP451
  4.   KumarA, Khurana D, Kaur S, Ghai S, Modi M, Pttanaik S, et al. “Post Stroke complications andcaregivers’ stress among stroke patients in a developing country” EuropeanStroke Journal 2019, Vol. 4(1S) 3–95. DOI: 10.1177/2396987319845560.
  5. Got2nd best paper award (Oral Presentation entitled, “StrokeHome Care’ a mobile based educational intervention for the prevention of poststroke complications among bedridden stroke survivors in developing country:Study Methodology”) in 1stNational Conference of IAMBSS-2019 held at PGIMER, Chandigarh

3. Mr. Mukesh Kumar

Status-Completed (Degree awaited)

Medical therapy used in major trials onextra cranial symptomatic carotid stenosis would be suboptimal now. Majority of these patientsmay fare well on optimal medical therapy (OMT) and therefore, surgery is believed to beunnecessary in a subset of patients.

Mr.Mukesh aimed to develop a risk prediction modeland to identify ESCS patients with highenough risk to warrant prophylacticintervention.

 

4.Ms.Pratiti Banerjee

Status-Completed (Degree awaited)

Pratiti comes from a background of Medical Biotechnology with thorough experience in wet stem cell oncology and molecular biology.Her project focused on developing a biomarker based diagnostic model to predict the onset of progression and neuro degeneration in Multiple Sclerosis patients. She was also involved in various intramural projects based on diagnosis and treatment of Multiple Sclerosis and is an integral part of management of the Multiple Sclerosis (MS) Clinic and patient outreach program MoveStrong, designing and management of the Move Strong website and management of International MS registry MSbase. Pratiti was the recipient of the prestigious Du Pre Grant 2017 granted to three research scholars globally each year by Multiple Sclerosis International Federation (MSIF) to carry out translational research in Multiple Sclerosis in a country other than the one currently working in through which she worked as a Visiting Scientist in the Department of Translational Neurology, Muenster University Hospital, Germany for a period of 110days. She has also presented her work in various national and global conferences. For detailed publication and achievement list please follow the link https://www.linkedin.com/in/pratiti-banerjee-3b180bb0/

5.Ms.Gurkeerat Kaur

Status- Ongoing

Gurkeerat Kaur also hails from a basic science background with experience in basic neuroscience. Her project focuses on the characterization of gut microbiota in Indian MS patients.

6.Ms.Mandeep Kaur

Status- Ongoing

Mandeep Kaur has a background of Physiotherapy (Neurology) and is currently working on Stroke Rehabilitation.
      Area Of
      Specialization      		 :
  1. Stroke
  2. Multiple Sclerosis
      Future Plans       :
.
      Awards & Honours       :

Research awards

·       Stroke Rehabilitation Award of International Stroke Conference 2020 at Los Angeles, USA Feb 2020 : Research award  results for the abstract: Medical Application based Post Stroke care Strategy for survivor and their caregivers (MAPSS): A Randomized Control Trial]

 

·       Paul Dudley White Award of the American Heart Association for the highest rated abstract at the International Stroke Conference 2020 at Los Angeles,USA. Feb 2020

 

 

·       Skoch Transformational Innovation Award – Top 100 at Delhi – presented the research work on innovative code stroke – The effect of electronic private automatic branch exchange (EPABX) system based stroke on the quality of acute stroke treatment

 

·       Practicing Physician Quality award 2014 of the American Academy of Neurology at 66th Annual Meeting of AAN; 26thApr – 3rd May 2014; Pennsylvania Convention Centre; Philadelphia USA.

 

·       Finalist for the BMJ Awards India 2014 in the category - Excellence in Medical Education.

 

·       Paper selected for best innovations at PGI Annual Research Day-2014

·       American Academy of Neurology-International affairs committee award -1998 (Co-author)

 

Other awards

·       Association of Indian Neurologists in America Appreciation Award at Washington in April 2014.

·       Thesis Guide and Supervisor of 2012 ISA (Indian Stroke Association) best Oral paper award recipient, Praveen Kesav.

·       Thesis Guide and Supervisor of 2014 ISA (Indian Stroke Association) runner up Oral paper award recipient, Gayathri Petluri.

·       Best paper award at the 8th  annual meeting of Indian Academy of  Neurology, held at Madurai in September 2000

·       Visiting Physician: Comprehensive Stroke Center, UAB, Birmingham, Alabama, USA and University Medical Center Ljubljana, Slovenia

·       Reviewer for Journal of Neurology, Neurosurgery and Psychiatry , Neurology, Journal of Neuroimaging, Neurology India  and  Annals of Indian Academy of Neurology

 

 

Fellowships:

·       IBRO (International Brain Research Organization) grant award for Brain awareness activities successively in 2005, 2006, 2008, 2009 and 2010         

 

·       Fellowship awarded to attend the ESO (European Stroke Organization) Stroke Summer School At the Lille University, Lille, France.September 2009 

 

·       Fellowship award to attend the 10th summer school of Myology at the La Salpeterier Hospital in Paris, France. June 2007

 

·       Traveling Fellowship of the International Stroke Society to attend the World Stroke conference at Cape Town, South Africa. October 2006

 

·       Fellowship of the World congress of Neurology to attend the 18th World Congress of Neurology at Sydney, Australia. Nov. 2005

 

·       IBRO fellowship for the 130th American Neurological Association at San Diego ,USA. September 2005

 

·       Traveling fellowship of the World Congress of Neurology for the 5th World congress at Vancouver BC, Canada.June 2004

 

·       Traveling fellowship of the International headache congress for the IHC at Rome in September 2003

 
      Member Of Professional
      Bodies      		 :

¡ñ     Member - American Academy of Neurology

¡ñ     Professional Member ¨C American Stroke Association

¡ñ     Member ¨C European Stroke Organisation

¡ñ     Member- World Stroke Organisation

¡ñ     Member - European Atherosclerosis Society

¡ñ     Life Member- Indian Stroke Association

¡ñ     Life Member of the Indian Academy of Neurology (IAN)

¡ñ     Life Member of the Neurological Society of India (NSI)

 
     
 :: Publications(In Vancouver Style)

For Complete list of his publications:-

http://www.researchgate.net/profile/Dheeraj_Khurana