Dr. Vivek Sagar
Designation : Associate Professor
Department : Community Medicine and School of Public Health
sagar.vivek@pgimer.edu.in , vivekgenetics@gmail.com

 
 
 :: Educational Qualification
  Graduation :   BSc Medical from DAV college Chandigarh in year 1998
  Post Graduation :   MSc Biotechnology from Kurukshetra University Kurukshetra in year 2000
  Other Qualification.(1)      :   Post Doc from HZI Germany in year 2012
     
 :: Area of Interest
       Area Of Interest       :
Molecular epidemiology and genomics for understanding the genetic evolution and pathogenesis of bacteria.
     
 :: Research & Projects
      Extramural Projects       :

1. Pneumococcal Vaccine Impact Assessment Study in Haryana, India: Co-PI

2. Prevalence and antibiotic resistance profile of Streptococcus pyogenes in Shillong and its association with RHD : Co-PI
      Departmental / P.G.I.
      Projects      		 :

To unravel evolutionary emergence of virulence in emm1-2 Group A Streptococcal strains isolated from throat, skin and blood by comparative genomics.
      Research In
      Progress      		 :
Evidence based advocacy of quick point of care nucleic acid-based detection method for diagnosis of acute covid emergency cases in hospital settings
      Area Of
      Specialization      		 :
Molecular Epidemiology and Genomics
      Future Plans       :
Point of care molecular diagnostics and implimentation of whole genome and microbiome approach to understand the genetic evolution and pathogeneis of pathogenic bacteria.
      Member Of Professional
      Bodies      		 :
ASM
     
 :: Publications(In Vancouver Style)

 

  1. Nandi S, ChakrabortiA, Bakshi DK, Sagar V, Kumar R andGanguly  NK. Genotyping of Group AStreptococcus by various molecular methods. Indian Journal of MedicalResearch (2002), 127,71-77.

  2. Sagar V, Bakshi DK,Nandi S, Ganguly NK, Kumar R and Chakraborti A. Molecular heterogeneity amongNorth Indian isolates of Group A Streptococcus. Letters in AppliedMicrobiology (2004)39, 84-88.

  3. Sagar V, Kumar R,Ganguly NK, Menon T and Chakraborti A. Distantly related sic (drs) is lessdivergent then SIC. Journal of Bacteriology (2007) 189, 2933-2935.

  4. Sagar V, Kumar R,Ganguly NK and Chakraborti A. Comparative analysis of emm type pattern of Group A Streptococcus throat and skin isolatesfrom India and their association with closely related SIC, a streptococcalvirulence factor. BMC microbiology (2008)8, 150.

  5. Kumar R, Vohra H, ChakrabortiA, Sharma YP, Bandhopadhya S, Dhanda V, Sagar V, Sharma M, Shah B,Ganguly NK. Epidemiology of Group A Streptococcal Pharyngitis and Impetigo: ACross Sectional and Follow-up Study in a Rural Community of Northern India. IndianJournal of Medical Research (2009), 130, 765-771.

  6. Bakshi DK, Dhanda V, SagarV, Toor D, Kumar R, Chakraborti A. emm 81, The Predominant Group AStreptococcus from North India in Year 2003 in Context to Adhesion, Invasionand Antimicrobial Susceptibility Pattern. J Bacteriol Parasito (2010).

  7. Kumar R, Chakraborti A, Aggarwal AK, Vohra H, Sagar V, Dhanda V,Sharma YP, Majumdar S, Hoe N, Krause RM. Streptococcus pyogenes pharyngitis and impetigo in a rural area of Panchkuladistrict in Haryana, India. IndianJournal of Medical Research (2012),135, 133-136.

  8. Bergmann R, Sagar V, NitscheP and Chhatwal  G. S. Firstdetection of trimethoprim resistance determinant dfrG inStreptococcus pyogenes clinical isolates in India. Antimicrobial Agents and Chemotherapy (2012), 56, 5424-5425.

  9. Sagar V, Bergmann R, Nerlich A, McMillan D.J, NitscheP and Chhatwal  G. S. Variability in thedistribution of genes encoding virulence factors and putative extracellularproteins of Streptococcus pyogenes inIndia, a region with high streptococcal disease burden, and implication ofdevelopment of a regional multi-subunit vaccine. Clinical and Vaccine Immunology (2012) 19, 1818-1825.

  10. Sharma A, Arya D.K, Sagar V, BergmannR, Chhatwal  G. S and Johri A.K. Identification ofpotential universal vaccine candidates against group A streptococcus by usinghigh throughput in silico and proteomicapproach. Journal of Proteome Research (2013) 12, 336-346.

  11. Sagar V*, Nerlich A,Bergmann R,  Nitsche P,. McMillan D.J,Geffers R, Hoe N, Kumar R, Nitsche P, Fulde M, Talay S, Rohde M,. Chakraborti A. and Chhatwal  G. S. Differences in   virulence repertoire and cell invasivepotential of group A Streptococcus emm1-2 in comparison to emm1 genotype. InternationalJournal of Medical Microbiology (2014) 304, 685-695.

  12. Rastogi M,Sagar V, Kumar R and Chakraborti A. Rheumatic Heart Disease(RHD): Prevention and Control in North India: Addressing the Challenges. Annals in Cardiovascular disease (2016), 1, 1015-1018.

  13. Sarkar S,Rastogi M, Choudhary P, Kumar R, Arora P, Sagar V, Sahni IP, Sethi S,Thakur K, Ailawadhi S, Toor D, Chakraborti A. Association of rheumaticfever and rheumatic heart disease with plausible early and late stage diseasemarkers: A comprehensive study. Indian Journal of Medical Research (2017),145, 758-766.

  14. ChaudharyP, Kumar R, Sagar V, Sarkar S, Kaur R, Ghosh S, Singh S and ChakrabortiA.   Assessment of Cpa, Scl1 andScl2 in clinical Group a streptococcus isolates and patients from north India:A study to evaluate host pathogen interaction. Researchin Microbiology (2018) 169, 11-19.

  15. Chauhan CK,Lakshmi PVM, Sagar V, Sharma AK, Arora SK and Kumar R. Primary HIV DrugResistance among recently infected cases of HIV in North-West India. AIDS research and Treatment (2019).

  16. MurhekarMV, Kamaraj P, Muthusamy SK, Khan SA, Allam RR, Barde P, Dwibedi B, Kanungo S, MohanU, Mohanty SS, Roy S, Sagar V,Savargaonkar D et al, Dengue working group. Burden of dengue infection inIndia, 2017: results from a cross-sectional population based serosurvey. The Lancet Global Health (2019) 7, e1065-e1073.

  17. ShuplerM,  Hystad P, Gustafson P, RangarajanS,  Mushtaha M,  Jayachitra, KG, Mony  P, Mohan D, Kumar P, Lakshmi PVM, Sagar V et al Household, community,sub-national and country-level predictors of primary cooking fuel switching innine countries from the PURE Study. EnvironmentalRes letters (2019) 14, 085006.

  18. Chauhan CK,Lakshmi PVM, Sagar V, Sharma AK, AroraSK and Kumar R. Using Immunological Markers Identifying Recent HIV Infection innorth west India. Indian J of Medical Research,(2020), 152, 227-233.

  19. MangtaniP, Berry I, Beauvais W, Holt HR, Kulashri A, Bharti S, Sagar V , Nguipdop-Djomo P, Bedi J, Kaur M, Guitian J, McGiven J,Grover GS , Kumar R. The prevalence and risk factors for human Brucella speciesinfection in a cross-sectional survey of a rural population in Punjab, India. Transactions of The Royal Society ofTropical Med. & Hygiene, (2020),1-9.

  20. Kaur H,Choudhary P, Khanna P, Singh T, Sagar V. Hidden food safety attributesand sensory evaluation of food served under mid-day meal scheme in khamanonblock, District Fatehgarh Sahib, Punjab (India). Applied Biological Research(2020), 22, 78-82.

  21. Sagar V*, ChkarbortiA and Kumar R. Whole genome sequence of Indian group A Streptococcus emmtype 1-2 strain isolated from blood sample from North India. MicrobiologyResource Announcements(2020, Vol 9, issue 19).

  22. Khaiwal R,Sagar V, Vij J, Kulashri A, Kaur M, Padhi, Singh A. Rapid Preparation ofHand Sanitizer using WHO Formulation in Hospitals during Restricted Supplyduring COVID-19 Pandemic. JPMER, (2020).

  23. MurhekarMV, Muthusamy SK, Kamaraj P, Khan SA, Allam RR, Barde P, Dwibedi B, Kanungo S,Mohan U, Mohanty SS, Roy S, Sagar V,Savargaonkar D et al, Dengue working group.Hepatitis-B virus infection in India: Findingsfrom a nationally representative serosurvey, 2017-18. International Journalof Infectious Disease (2020).

  24. Shupler M,Hystad P, Birch A, Miller-Lionberg D, Jeronimo M,  Arku RE, YLChu, Mushtaha M, Heenan L, Rangarajan S, Seron P, Lakshmi PVM, SagarV....et all. Household and Personal Air Pollution Exposure Measurementsfrom 120 Communities in 8 Countries: Results from the PURE-AIR Stud. TheLancet Plenary Health, October (2020).

  25. MuthusamySK, Kamaraj P, Khan SA, Allam RR, Barde P, Dwibedi B, Kanungo S, Mohan U,Mohanty SS, Roy S, Sagar V,Savargaonkar D et al Seroprevalence of chikungunya virus infection in India, 2017: across-sectional population-based serosurvey. Lancet Microbe 2021.

  26. Kaur G,Gupta M,  Aggarwal A, Sagar V*. Diagnosisof COVID-19:An evolution from hospital based to point of care testing. J ofCommunity Medicine and Public Health 2021.

  27. Sagar V*, Kaur G, Sharma A,Nadda A, Aggarwal A. Exploratory Sero prevalence of SARS-CoV-2 (Covid -19)among health care professionals in Department of Community Medicine & Schoolof Public Health (PGIMER, Chandigarh) J of Community Medicine and PublicHealth 2021.

  28. MurhekarMV, Kamaraj P, Muthusamy SK, Khan SA, Allam RR, Barde P, Dwibedi B, Kanungo S,Mohan U, Mohanty SS, Roy S, Sagar V,Savargaonkar D et al, Dengue working group. Immunity against diphtheria amongchildren aged 5–17 years in India, 2017–18: a cross-sectional, population-basedserosurvey. The Lancet Infectious Diseases 2021.

  29. AggarwalAK, Nadda A, Gupta U, Sagar V, Sharma A, Monga D. RealtimeSupervision and Quality Assessment of State-wide Community basedSero-Surveillance for Anti-Sars-Cov-2 IgG Antibodies. International Journal ofHealth Systems and Implementation Research, 2022.