• Pathophysiology of coronary artery disease at cellular & molecular level.
• Nutrigenomics: Nutrient-gene interaction studies in the modulation of coronary artery disease by using indigenous herbal medicinal plants with therapeutic potential.
• Biomarkers of environmental pollution.

(1) Modulation of inflammatory process by non-coding RNAs and epigenetic modifications in patients with coronary artery disease.

• Pathophysiology of coronary artery disease at cellular & molecular level.

• Nutrigenomics: Nutrient-gene interaction studies in the modulation of coronary artery disease by using indigenous herbal medicinal plants with therapeutic potential.

Best Research Work:

Ø  “MAJOR GENERAL AMIR CHAND GOLD MEDAL” Award, PGIMER, Chandigarh : Mahajan N, Bahl A, Dhawan V. “C-reactive protein (CRP) up-regulates the expression of receptor for advanced glycation end products (RAGE) and its inflammatory ligand EN-RAGE in THP-1 cells: Inhibitory effects of Atorvastatin”. Int J Cardiol 2010 Jul 23;142 (3):273-8. 

Ø  “V. K. SAINI GOLD MEDAL” Award,  PGIMER, Chandigarh:

“Mahajan N, Malik N, Bahl A, Dhawan V. “Receptor for advanced glycation end products (RAGE) and its inflammatory ligand EN-RAGE in non-diabetic subjects with premature coronary artery disease.”. Atherosclerosis 2009Dec;207(2):597-602.

Ø  “MAJOR GENERAL AMIR CHAND BRONZE MEDAL” Award, PGIMER, Chandigarh:

Sharma I, Dhawan V, Mahajan N, Saha SC, Dhaliwal LK. In vitro effects of atorvastatin on LPS-induced gene expression in endometriotic stromal cells. Fertil Steril 2010 Oct; 94 (5):1639-1646.e1.

Best paper awards : National Conference :

v  Oral Presentation (I am a co-author) : K Vaiphei, A Khaliq, p Rajguru, U Dutta, R Kocchar, Dhawan V, K Singh. “A correlative analysis of the histomorphological spectrum in duodenal biopsy of adult celiac disease with epithelium functional state and autophagy in antigen presenting dendritic cells” in a plenary session in “The 52^nd Annual Conference of The Indian Society of Gastroenterology” held   at Kolkata on 9^th December, 2009.

v  Best Paper Award : (As a Corresponding-Author) :   Oral Presentation :

Sharma I, Dhawan V, Saha S and Dhaliwal L. “Role of 8-Iso-PGF2alpha and 25-Hydroxycholesterol in the pathophysiology of endometriosis” in “The National Conference on Infertility, “ FERTIVISION-2006”  at India Habitat Centre, New Delhi from 9^th-10^th, December, 2006. 

1.      Dhawan V, Ganguly NK, Majumdar S, Chakravarti RN. Short-term Therapy ofatherosclerosis with low dose indomethacin. An experimental study. J MedPrimatol USA 1990;19:663-673.

2.      Dhawan V, Sharda N, Majumdar S, Ganguly NK, Chakarvati RN. Platelet aggregabilityand serum thromboxane level in hypercholesterolemic atherosclerotic monkeys. MedSci Res 1990; 18:149-151.

3.      Chandra K, Gupta I, Dhawan V, Ganguly NK. Prostaglandin F2 alpha levels in normal saline induced midtrimeseter abortions. Contraception 1991; 44:99-106.

4.      Dhawan V, Majumdar S, Ganguly NK, Chakravarti RN. Effect of indomethacin on serumlipids, lipoprotiens, prostaglandins and the extent and severity ofatherosclerosis in monkeys. Can J Cardiol 1992; 8(3):306-312.

5.      Ganguly NK, Nalini K, Dhawan V, Meenakshi S and Chakravarti RN. Free radicals in myocardial injury.Experimental and Clinical studies. Molecular and Cellular Biochemistry1992;111:71-76.

6.      Kaul D. Dhawan V, Singh M.Evidence and nature of a thiol oxidase in human platelets. Mol Cell Biochem1996, 159: 81-84.

7.      Chaudhari S, Verma M, Dhawan V, Nain CK, Kumar R, Kumar L,Ganguly NK. Vitamin A, Zinc andSelenium levels in children with acute and persistent diarrhea. J DiarrhealDiseases Research 1996; 14(3).

8.      Suri RK, Ratna MS, Dhawan V, Gupta A, Gupta R, Sharma K, Thingam SKS, Puri G D, Madhulika S, GangulyNK . Reactive Oxygen Species. Ann N Y Acad Sci Myocardial Reperfusion 1996;793: 66-370.

9.      Ganguly NK , Kaul N, Wahi S, Dhawan V, Sharma M, Chakravarti RN. Possible role of oxygen free radicals inmyocardial infarction and atherosclerosis. Mol Cell Biochem 1992;112:1303-1308.

10.  Kaul D, Kaur M, Dhawan V. Humanplatelets contain a Novel 47 KDa Thiol-oxidase having affinity for genomicsterol-regulatory sequence. Molecular and Cellular Biochemistry 1998:178,   383-385. 

11.  Agnihotry N, Kaur U, Dhawan V, Bhasin S, Experimental extrahepatic portal hypertensivegastropathy in wistar rats: Modulation of acid secretion in isolated parietalcells. Digestive Diseases and Sciences 1997: 97 pp 116.

12.  Dhawan V, Chaudhary S, Verma M, Nain CK, Kumar R, Kumar L, Ganguly NK. Effect ofvitamin A deficiency and supplementation on micronutrient status: A study inslum children. J Diarrheal Diseases Research 1998.

13.  Mehta Alka, Singh S, Dhawan V, Ganguly N.K. Intestinal mucosal lipid peroxidation and absorptivefunction in S. typhimurium mediatedintestinal infection. Mol Cell Biochem 1998;178:345-352

14.  Kaur Tanvir, Singh S, Dhawan V, Ganguly NK. Shigella dysenteriae type 1 toxin-induced lipidperoxidation in enterocytes isolated from rabbit ileum. Mol Cell Biochem1998;178: 169-179.

15.  GuptaG, Gupta I, Suri V, Dhawan V, Ganguly NK. Estimation of cordblood erythropoeitin in pre-eclampsia and eclampsia. Int J Gynae Obstet 2000;71(1):1-5.

16.  RameshG, Varma JS, Bali HK, Singh M, Dhawan V, Ganguly NK. Increasedplasma nitric Oxide in Cardiac Failure. MolCell Cardiol 1999;31(8):1495-1500.

17.  RameshG, Jindal SK, Ganguly NK, Dhawan V. Increased nitric oxideproduction by neutrophils in bronchical asthma. Eur Respir J 2001;17:868-871.

18.  TandonS, Kaur U, Dhawan V, Singh K. Gastropathy and defence mechanismin common bile duct ligated portal hypertensive rats. Mol Cell Biochem 2000;203:79-85.

19.  Das S, Mahajan RC, Ganguly NK, Sawhney IMS, Dhawan V and Malla N. Detection of antigen B of C. Cellulosae in cerebrospinalfluid for the diagnosis of human neurocysticercosis. Tropical Medicine andInternational Health 2002;7(1):53-58.

20.  Attri J, Dhawan V, Mahmood S,Pandhi P, Parwana HK, Nath R. Effect of vitamin C supplementation on oxidativeDNA damage in an experimental model of lead-induced  hypertension. Ann Nutr Metab 2003;47(6).

21.  Dhawan V, Sanjay Jain. Effect of Short-term garlic supplementation on oxidizedlow density lipoprotein and lipid peroxidation in patients of essentialhypertension. Mol Cell Biochem 2004; 266: 115-119.

22.  Dhawan V, Handu SS, Nain CK and Ganguly NK. Chronic L-arginine supplementation improves endothelial cell vasoactive functions inhypercholesterolemic and atherosclerotic rhesus monkeys. Mol Cell Biochem2005;269:1-11.

23.  Rawal S, Majumdar S, Dhawan V, Vohra H. Entamoeba histolytica Gal/GalNac lectin depletes antioxidantdefences of target epithelial cells. Parasitology 2004;128:6.

24.  DhawanV, Sanjay Jain. Garlicsupplementation prevents Oxidative DNA damage in patients of essentialhypertension. Mol Cell Biochem 2004;266(1-2):109-115.

25.  Navada M, Gupta I, Dhawan V, Sharma M, Majumdar S. Observations on reactive   molecules and microorganisms during use of acopper IUCD. Int J Obst Gyne 2005;89(3):282-3.

26.  Sood S, Rishi P, Dhawan V, Sharma S,Ganguly NK. Protection mediated by antibodies to iron regulated outer membraneproteins of S. typhi in a mouse peritonitis model. Mol Cell Biochem2005;273: 69-78.

27.  Kaul D, Shukla AR, Sikand K, Dhawan V. Effect of herbal polyphenols on atherogenic transcriptome. Mol CellBiochem 2005;278 (12):177-84.

28.  Dhawan V, Mahajan N, Jain S. Role of C-C chemokines in Takayasu’s ArteritisDisease. Int J Cardiol 2006;111:115-119.

29.  Mahajan N, Dhawan V, Sharma G,Jain S, Kaul D. Effect of green tea polyphenols on inflammation and vascularremodeling in normocholesterolemic virgin hypertensives. J Hum Hypertension2008;22:141-143.

30.  Aggarwal A, Medhi B, Dhawan V,Chakrabarti A. Neuroprotective effect of progesterone on acute phase changesinduced by partial global cerebral ischemia in mice. J Pharmacy andPhamacology 2008;60:731-737.

31.  Malik N, Dhawan V, Bahl A, KaulD. Inhibitory effects of Terminaliaarjuna on platelet activation invitro in healthy subjects and patients with coronary artery disease. Platelets2009; 20(3):1-8.

32.  Mahajan N, Malik N, Bahl A,Sharma YP, Dhawan V. Correlation among soluble markers and severity of diseasein non-diabetic subjects with premature coronary artery disease. Mol Cell Biochem 2009 Oct;330(1-2):201-9. 

33.  MahajanN, Bahl A, Dhawan V. C-reactive protein (CRP) up-regulates theexpression of receptor for advanced glycation end products (RAGE) and itsinflammatory ligand EN-RAGE in THP-1 cells: Inhibitory effects of Atorvastatin.Int J Cardiol 2010 Jul 23;142(3):273-8. 

34.  Sharma I, Dhaliwal LK, Saha SC, Sangwan S, DhawanV. Role of 8-iso-prostaglandin F2α and 25-hydroxycholesterol in thepathophysiology of endoemetriosis. Fertil Steril 2010 Jun;94(1):63-70.

35.  MahajanN, Malik N, Bahl A, Dhawan V.RAGE-EN-RAGE axis in non-diabetic subjects with premature coronary arterydisease. Atherosclerosis 2009Dec;207(2):597-602.

36.  Sharma I, Dhawan V, Mahajan N,Saha SC, Dhaliwal LK. In vitro effectsof atorvastatin on LPS-induced gene expression in endometriotic stromal cells. Fertil Steril 2009. DOI: 10.1016/j.fertnstert.2009.10.003

37.  MahajanN, Dhawan V, Malik S, Jain S.Implication of Oxidative Stress and its correlation with activity of matrixmetalloproteinases in patients with Takayasu’s Arteritis Disease. Int J Cardiol 2009.DOI:10.1016/j.ijcard.2009.09.557.

38.  MahajanN, Dhawan V. Inhibition of C-reactiveprotein induced expression of matrixmetalloproteinases by atorvastatin in THP-1 cells. Mol Cell Biochem2010 May;338(1-2):77-86.

39. Mittal A, Mahajan N, Vijayvergiya R, Dhawan V. Modulation of GeneExpression by Polyalthia longifoliain Postmenopausal Women with Coronary Artery Disease: An In Vitro Study.  J Cardiovasc Trans Res 2009DOI:10.1007/s12265-009-9162-1

40. MahajanN, Bisht D, Dhawan V, Singh S, Minz RW. Transcriptionalexpression and gelatinolytic activity of matrix metalloproteinases in Henoch-SchonleinPurpura. Acta Paediatrica 2010 Aug; 99(8):1248-52.

41. SharmaI, Dhawan V, Saha SC, Bagga R, Dhaliwal LK. Implication ofRAGE-EN-RAGE axis in endometriosis. Int J Gynecol Obstet 2010 Sep;110(3):199-202.

42. Mahajan N, DhawanV. In vitro modulation ofperoxisome proliferator activated receptor-γ (PPAR-γ) and its effector genes byC-reactive protein (CRP): Effect of atorvastatin. Arch Med Res 2010 Apr;41(3):154-161.

43. SharmaI, Dhawan V, Saha SC, Dhaliwal LK. In vitro effects of PPAR-γ ligands ongene expression in LPS-induced endometrial and endometriotic stromal cells.FertilSteril 2011 Feb; 95 (2): 829-831.e5.

44. KalpdevA, Saha SC, Dhawan V. Vitamin C and E supplementation does notreduce the risk of superimposed PE in pregnancy. Hypertension in Pregnancy2011; 30(4):447-56.

45. Dave VP, Kaul D, Sharma Y, Bhattacharya R, Dhawan V. Mutated LXR- α gene within Blood MononuclearCells of CHD Patients: Significance of Serum Factors. J Clinic Experiment Cardiol. 2011. doi: 10.4172/2155-9880.100125

46. Mahajan N, Dhawan V, Mahmood S, Malik S, Jain S. Extracellular matrix remodeling inTakayasu's arteritis: role of matrix metalloproteinases and adventitialinflammation. Arch Med Res. 2012 Jul;43(5):406-10.

47. Mahajan N, Dhawan V.Potential biomarkers for disease activity in Takayasu's arteritis. Int J Cardiol. 2012 Jul 12; 158(2):331.

48.  Mahajan N, Mahmood S, Jain S, Dhawan V. Receptor for advanced glycation end products(RAGE), inflammatory ligand EN-RAGE and soluble RAGE (sRAGE) in subjects withTakayasu's arteritis. Int J Cardiol. 2013 Feb 8. (DOI:10.1016/j.ijcard.2013.01.002). 

49. Mahajan N, Dhawan V. Receptor foradvanced glycation end products (RAGE) in vascular and inflammatory diseases. Int JCardiol. 2013 May 27. pii:S0167-5273(13)00922-4. doi: 10.1016/j.ijcard.2013.05.013.

50. Nitin Mahajan, Divya Kapoor, DineshBisht, Surjit Singh, Ranjana W Minz, VeenaDhawan. "Levels of IL-18 and ET-1in children with Henoch Schonlein Purpura: A study from North India".Pediatric Dermatology ID PEDDERMJ-13-175.R1.

51. Mahajan N, Dhawan V. Receptor for advancedglycation end products (RAGE) in atrial fibrillation. Int JCardiol. 2013 Oct 3;168(3):1788-94.

52. VeenaDhawan, Harsimran Sidhu. Statins: are they wonder drugs?. Br J Cardiol 2014;21: 40 (doi: 10.5837/bjc.2014.008).

53. Owais Mohammad Bhat, P Uday Kumar, NVGiridharan, Deepak Kaul, MJ Mahesh Kumar, VeenaDhawan. Interleukin-18-inducedatherosclerosis involves CD36 and NF-κB crosstalk in Apo E−/− mice. Journal of cardiology, Volume: 66, Issue:1, Pages: 28-35.

54. Riyaz Ahmad Rather, Subhas Chandra Saha, Veena Dhawan. The MostFavourable Procedure for the Isolation of Cell-free DNA from the Plasma ofIso-immunized RHD-negative Pregnant Women (in Press) J. Circ. Biomarkers DOI : 10.5772/62113

55. Sanjay Jain, Benzeeta Pinto, Naveen Kalra, Veena Dhawan. RelationshipBetween Inflammation and Endothelial Dysfunction in Essential Hypertension. Journalof Hypertension: Volume: 33, Pages: e4.

56. Divya Kapoor, Dimple Trikha, RajeshVijayvergiya, KK Parashar, Deepak Kaul, VeenaDhawan. Short-TermAdjuvant Therapy with Terminalia arjuna Attenuates Ongoing Inflammation andImmune Imbalance in Patients with Stable Coronary Artery Disease: In Vitro andIn Vivo Evidence. Journal ofcardiovascular translational research:

Volume: 8, Issue: 3, Pages: 173-186.

57. Owais Mohammad Bhat, Veena Dhawan. Role of IL-18and its signaling in atherosclerosis. Inflammation and Cell Signaling :Volume: 2, Issue: 1, e707.

58. VDhawan, R Rather, D Trikha, V Malik, C Bakshi. Proteomicanalysis of differential protein expression in high fat diet-inducedhypercholesterolemic rabbits. Atherosclerosis: Volume: 241, Issue: 1, Pages: e32.

59. R Rather, VDhawan, D Trikha. Effect ofethanolic fraction of Terminalia arjuna on      inflammatory markers in hypercholesterolemic rabbits. Atherosclerosis.241 (1) pp e55-e56.

60. O Bedi, V Dhawan, PL Sharma, P Kumar. Pleiotropic effects of statins: new therapeutictargets in drug design. Naunyn-Schmiedeberg'sarchives of pharmacology 389 (7), 695-712.

61. S Jain, N Rao, N Kalra, V Dhawan. MPS 03-09 inflammation and severity of carotidatherosclerosis in metabolic syndrome. Journal of Hypertension 34, e86.

62. RA Rather, VDhawan. Genetic markers: Potential candidates forcardiovascular disease. InternationalJournal of Cardiology 220, 914-923.

63. JS Thakur, B Bharti, JP Tripathy, V Dhawan, A Bhansali. Impact of 20 Week Lifestyle Intervention Package onAnthropometric Biochemical and Behavioral Characteristics of Schoolchildren inNorth India. Journal oftropical pediatrics 62 (5), 368-376.

64.  OM Bhat, PUKumar, N Harishankar, L Ravichandaran, A Bhatia, V Dhawan. Interleukin-18-induced cell adhesion moleculeexpression is associated with feedback regulation by PPAR-γ and NF-κB in ApoE−/− mice. Molecularand Cellular Biochemistry, 428 (1-2),119-128.

65.  A Sandhu, VDhir, A Bhatnagar, V Dhawan,J Kaur, A Sood, S Naidu, S Ahmad, N Varma, ASharma, S Sharma. High Methotrexate Triglutamate Level is an independentpredictor of adverse effects in Asian Indian Rheumatoid Arthritis Patients-APreliminary Study. TherapeuticDrug Monitoring.

66.  RVijayvergiya, D Kapoor, A Aggarwal, S Sangwan, V Suri, V Dhawan. Analysis of traditional and emergingrisk factors in premenopausal women with coronary artery disease: A pilot-scalestudy from North India. Molecular and Cellular Biochemistry, 1-1.

67.  CSingh, S Jain, V Dhawan, NKalra, S Kumari. [lb. 02.26] Association Of Serum UricAcid And Endothelial Dysfunction In Patients With Metabolic Syndrome.Journal of Hypertension 35, e257-e258.

68.  SBhansali, A Bhansali, V Dhawan.Metformin regulates mitophagy through AMPK signallingpathway in human-derived mononuclear cells. DIABETOLOGIA 60,S141-S142

69.  ASandhu, V Dhir, S Ahmad, P Kaur, V Dhawan, A Bhatnagar. Decline in CD8+ IFN gamma plus Subset but Rise in CD8+IL17+ on Methotrexate Treatment in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY 69.

70.  SBhansali, A Bhansali, V Dhawan.Favourable metabolic profile sustains mitophagy andprevents metabolic abnormalities in metabolically healthy obese individuals.Diabetology & metabolic syndrome 9(1), 99.

71.  SBhansali, A Bhansali, R Walia, UN Saikia, VDhawan. Alterations in mitochondrialoxidative stress and mitophagy in subjects with prediabetes and type 2 diabetesmellitus. Frontiers inendocrinology 8, 347.

72.  ASandhu, S Ahmad, P Kaur, A Bhatnagar, VDhawan, V Dhir. Methotrexate preferentially affectsTc1 and Tc17 subset of CD8 T lymphocytes. Clinical rheumatology,1-8.

73.  OMBhat, PU Kumar, KR Rao, A Ahmad, VDhawan. Terminalia arjuna preventsInterleukin-18-induced atherosclerosis via modulation of NF-κB/PPAR-γ-mediatedpathway in Apo E−/− mice. Inflammopharmacology26 (2), 583-598

74. 

NATIONAL

1.      Dash RJ. Broor Sl, Mehta V, Naik SR and Mehta SK. Gastrin radioimmunoassay “Serum gastrin levels inhealthy men and patients with chronic duodenal ulcer” Bull PGI1979;13(2):97-101.

2.      Dhawan V, Vaishnavi C, Nanda K, Kumar B, Kaur S, Ganguly NK. ProstaglandinF2-alpha in leprosy-A preliminary study. Ind J Leprosy 1990;62:45-50.

3.      Ganguly NK, Dhawan V, Kaul N,Chakravarti RN. Immunological aspects of atherogenesis. Current Trends inAtherosclerosis 1990.145-150.

4.      Sharda N, Dhawan V, Bansal N,Majumdar S, Chakravarti RN.  Role ofcirculating immune complexes and platelet aggregation in the development ofexperimentally induced atherosclerosis in monkeys with normal intact vasdeferens and following vasectomy. Ind Heart J 1991;43:35-38.

5.      Nain CK, Singh K, Munjal A, Dhawan V, Ganguly NK. Evaluation of antacid gel preparations availablecommercially in the market. Trop Gastroenterol 1992;13(2):70-74.

6.      Chakravarti RN, Dhawan V. Platelets, prostaglandins andatherosclerosis. Ann Natl Acad Med Sci 1991;27(1):1-12.

7.      Chakravarti RN, Dhawan V. Non-Humanprimates in cardiovascular research. Lab Animals India 1992:1(2):23:26.

8.      Chakravarti RN, Dhawan V. ExperimentalAtherosclerosis. Editorial. Ind Heart J 1992:43(5):351-355.

9.      Vaishnavi C, Dhawan V, GangulyNK, Sethi A, Kumar B. Hydrolytic enzymes in leprosy sera.  J  HygEpid Microbiol and Immunol 1992;36(4):401-404.

10.  Kaur U, Nain CK, Dhawan V, Bambery P.Sodium and Potassium content of liquid antacids. Ind J Gastroenterol1992;11(4):166-167.

11.  Chakravarti RN, Dhawan V.“Atherosclerosis” What is new? J Assoc Phys India, APICON 1993 (Sep.Dec.)

12.  Sawhney R. Gupta A, Bansal RR, Dhawan V, Ganguly NK, Aggarwal A. Eale’s Disease: An auto-immune retinaldisorder. Published in All India Opthalmological Society. Golden JubileeConference 1992, New Delhi in Proceedings. Editor. V. Kalevar

13.  Dhawan V, Ratan Kumar Kh, Ganguly NK AND Marwaha RK. RBC, Vitamin E andsuperoxide dismutase in β Thalassemia: A Clinical study. Indian Journal ofPediatrics 2005.

14.  K Haldar, I Gupta, Dhawan V, Prasad GRV, Majumdar S. correlation of amniotic fluid index and cordblood erythropoietin levels in small for gestational age new borns: BulletinPGI 2005;27-32.                                                                                                           

15.  Nain CK, Kaur U, Singh V, Dhawan V and Singh K Acetylsalicylic acid and induced biochemical changes in thegastric juice. Ind J Gastroenterol 1998;17:4-5.

16.  Dhawan V, Ratan Kumar Kh, Marwaha RK, Ganguly NK. Antioxidant status in Childrenwith Homozygous β Thalassemia. Indian Pediatrics. 2005;42:1141-1145.