Prof. Dheeraj Khurana
Designation : Professor
Department : NEUROLOGY
khurana.dheeraj@pgimer.edu.in

 

 
 :: Contact Details
  Phone No.    :   7087009695
  Ext No.        :   6695
 :: Educational Qualification
  Graduation :   MBBS from DMCH.Ludhiana in year 1992
  Post Graduation :   MD (Med) from DMCH.Ludhiana in year 1996
  Other Qualification.(1)      :   DM (Neurology) from PGIMER. Chandigarh in year 2000
     
 :: Area of Interest
       Area Of Interest       :
  1. Acute Stroke : Thrombolysis, imaging,management and rehabilitation
  2. Multiple Sclerosis : Management and rehabilitation
  3. Neurosonology : Carotid duplex, TCD and its applications


 
     
 :: Research & Projects
      Extramural Projects       :


ACADEMIC


S No

Title

Role

Sponsor

Status

1

SITS SEARES – Safe Implementation of Treatments in Stroke

National Co -ordinator

Non-funded

Ongoing

2

In-hospital database for Multiple Sclerosis - MS Base

Principle Investigator

Non-funded

Ongoing

3

INSTRuCT

I.                     Enhanced Control of Hypertension and Thrombolysis in Stroke Study – ENCHANTED

 

 

II.                   Secondary Prevention By Structured Semi-Interactive Stroke Prevention Package in INDIA (SPRINT INDIA) Study

Principle Investigator

 

George Institute, Hyderabad

 

ICMR

Ongoing

4

Head positioning in Stroke Trials - Head PoST

Principle Investigator

George Institute, Hyderabad

Recruitment Completed – 2017

 

5

FAmily- Led RehabiliTaTion aftEr stroke in INDia -The ATTEND trial

Principle Investigator

George Institute, Hyderabad

Recruitment Completed – 2016

 

6

INTERSTROKE - Importance of Conventional and Emerging Risk Factors for Stroke : A Case Control study

Principle Investigator

SJRI, Bangalore; NIH, USA

Completed - 2014

7

Indo-US Collaborative stroke Registry and Infrastucture development (US-India Bilateral brain research Collaborative partnerships)

Principle Investigator

DBT, India

Completed - 2014

8

Multi Centre Feasibility Pilot study: Safety and Feasibility Assessment of the Neuropath TM IS System in Treatment of Acute Ischemic Stroke-A Pilot Study

Principle Investigator

Brainsgate, Israel

Completed - 2009







Projects in Pipeline:


Sr No

Project

Role

Sponsor

Status

1

RESURRECT (REmote ISchemic conditioning and Fentanyl as an adjUnct to therapeutic hypotheRmia in Hypoxic ischEmic Brain Injury post Cardiac ArresT Study;HIBI Iinitiative)

Co-investigator

DBT

Pipeline

2

Development of low –cost robust hardware and software towards point of care monitoring (POCT) of neuro-glial –vascular interactions (especially inverse neuro-vascular  coupling) during spreading depolarisations in brain trauma using simultaneous  recording of EEG and NIRS.

Co-investigator

DST

Pipeline

 

 


 



DRUG TRIALS

 


  

S No

Title

Role

Sponsor

Status

1

Randomized, double-blind evaluation in secondary stroke prevention comparing the efficacy and safety of the thrombin inhibitor dabigatran etexilate 110 or 150 mg (twice daily) versus acetylsalicylic acid (100 mg once daily) in patients with embolic stroke of undetermined source (RE-SPECT ESUS)

Principle Investigator

Boehringer Ingelheim

ongoing

2

A randomized, double-blind, double-dummy, parallel-group study comparing the efficacy and safety of ofatumumab versus teriflunomide in patients with relapsing multiple sclerosis

Principle Investigator

Novartis

ongoing

3

A randomized, multicenter, placebo-controlled and active reference (glatiramer acetate) comparison study to evaluate the efficacy and safety of BG00012 in subjects with relapsing-remitting multiple sclerosis

Principle Investigator

Biogen Idec

Completed – 2011

4

A Dose-Blind, Multicenter, Extension Study to Determine the Long-Term Safety and Efficacy of Two Doses of BG00012 Monotherapy in Subjects With Relapsing-Remitting Multiple Sclerosis

Principle Investigator

Biogen Idec

Completed – 2017

5

A Randomised, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of desmoteplase in acute ischemic stroke

Principle Investigator

Lundbeck, Denmark

Completed - 2014

6

INTERACT-2 Intensive Blood Pressure Reduction in acute Cerebral Hemorrhage trial

Principle Investigator

George Institute, Hyderabad

Completed - 2012

      Departmental / P.G.I.
      Projects      
:

S No

Title

Role

Sponsor

Status

1

Development of a immuno-marker based predictive model for early detection and characterization of progressive multiple sclerosis

 

Principle Investigator

PGIMER, Chandigarh

Ongoing

      Research In
      Progress      
:

PhD program:

Current PhD Scholars:

 

 Jitender Gairolla (MSc Microbiology)

Jitender comes from the Microbiology background and is an ICMRscholar.His research deals with thegenetic variation analysis of adipokine genes in ischemic stroke. His otherfields of research are biomarker and antiplatelet drug discovery in the fieldof stroke, Neuromicrobiology, Development of Aerobic bacterial consortia forbioremediation of synaptic broad spectrum organophosphorus insecticide,Metabolomics profiling using HPLC and LCMS, Genotyping using Real-Time PCR andstatistical analysis. Mr.Gairolla has a significant number of publications torepresent his work and has also presented abstracts in both national andinternational forums.Publication and other details can be followed on https://www.linkedin.com/in/jitender-gairolla-25ba87111/

 

Ashok Jangir -  (MSc Nursing)

Coming from the nursingbackground, Ashok had been working as a stroke nurse. His research deals withdeveloping a smartphone app to train the caregivers of the bedridden strokepatients so that they can provide care to their patients at home andminimize  the post stroke complications.Mr.Jangir has a number of national and international publications to his nameincluding a book chapter and has also presented his work in variousconferences.

 

 

Pratiti Banerjee (MSc Medical Biotechnology)

Pratiti comes from abackground of Medical Biotechnology with thorough experience in wet stem celloncology and molecular biology.Currently she is working on developing a biomarker based diagnostic model topredict the onset of progression and neuro degeneration in Multiple Sclerosispatients. She is also involved in various intramural projects based ondiagnosis and treatment of Multiple Sclerosis and is an integral part ofmanagement of the Multiple Sclerosis (MS) Clinic and patient outreach program MoveStrong, designing and management of the Move Strong website andmanagement of International MS registry MSbase. Pratiti is the recipientof the prestigious Du Pre Grant 2017 granted to three research scholarsglobally each year by Multiple Sclerosis International Federation (MSIF) tocarry out translational research in Multiple Sclerosis in a country other thanthe one currently working in through which she will be working as a VisitingScientist in the Department of Translational Neurology, Muenster UniversityHospital, Germany for a period of 110days. She has also presented her work invarious national and global conferences. For detailed publication and achievement list please follow the link https://www.linkedin.com/in/pratiti-banerjee-3b180bb0/

 

      Area Of
      Specialization      
:
  1. Stroke
  2. Multiple Sclerosis
      Future Plans       :
.
      Awards & Honours       :

1.    American Academy of Neurology- Practising physician Quality Award- 2014

2.    Best paper award for the paper “Delayed CT ‘swirl sign’ Predicts Outcome in Intracerebral Haemorrhage” awarded to Dr Praveen Kesav mentored by Dr Dheeraj Khurana for his research at the annual ISA meeting- 9th National Conference (ISACON) 2014, Thiruvananthapuram, Kerala

 

      Member Of Professional
      Bodies      
:

¡ñ     Member - American Academy of Neurology

¡ñ     Professional Member ¨C American Stroke Association

¡ñ     Member ¨C European Stroke Organisation

¡ñ     Member- World Stroke Organisation

¡ñ     Member - European Atherosclerosis Society

¡ñ     Life Member- Indian Stroke Association

¡ñ     Life Member of the Indian Academy of Neurology (IAN)

¡ñ     Life Member of the Neurological Society of India (NSI)

 

     
 :: Publications(In Vancouver Style)

For Complete list of his publications:-

http://www.researchgate.net/profile/Dheeraj_Khurana